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Image Search Results
Journal: bioRxiv
Article Title: Harnessing micrometer-scale tPA beads for high plasmin generation and accelerated fibrinolysis
doi: 10.1101/2024.11.06.621942
Figure Lengend Snippet: Plasmin generation was measured using chromogenic substrate S-2251, glu-plasminogen, and 2.25 mU/mL tPA activity with ( A ) free tPA, ( B ) 0.1 μm t-PA beads, or ( C ) 1 μm tPA beads and its co-factors fibrinogen or fibrin degradation product (FDP) at 37°C. Each line and shaded region represent the average and standard deviation of n=3. ( D ) Slope of the reaction curves at 50% of the maximum absorbance for each condition. Bars and error bars represent the average and standard deviation of n=3. *, p < 0.001 represents significant difference between matching tPA conditions for a given co-factor (comparison of grouped blue, orange, and green bars). Δ, p < 0.001 represents the significant difference between co-factors for a given tPA condition (comparison of like colored bars).
Article Snippet: Purified human lys-plasmin (cat# IHUPLMLYS1MG) and
Techniques: Activity Assay, Standard Deviation, Comparison